The GlycoMark Test

For better control of diabetes. And a better life.

The GlycoMark test is a simple, non-fasting blood test that indicates blood glucose control over a one- to two-week period in people with diabetes. By measuring 1,5-anhydroglucitol (1,5-AG), a particular type of glucose-like sugar in your blood, the GlycoMark test can help identify high-glucose episodes. It’s what you don’t know now, and it’s important.

Hyperglycemia is more than a peak episode. It’s a threat.

Hyperglycemia is a condition where your blood sugar is at levels higher than your body can handle.  Glycemic variability also involves hyperglycemia—it is caused by spikes in glucose levels (hyperglycemia) followed by drops in glucose levels. In addition to the threat of diabetes complications, including kidney disease, retinopathy and cardiovascular events, long-term, persistently high glucose levels can decrease energy, alter your moods, and compromise brain function.

The goal of diabetes management is to maintain your blood glucose at a level your physician determines is best for your health. That means reducing major swings, such as high blood glucose after you eat or low blood glucose after you take your diabetes medication.

The more you and your doctor know about your blood glucose levels and the sooner you know it, the better you can control hyperglycemia for more effective management of diabetes. Among tests used for monitoring glycemic control, the GlycoMark test is the only specific indicator of recent hyperglycemic spikes. That’s why the GlycoMark test can be a valuable addition to your treatment and glucose monitoring regimen.

A1C can’t tell you all you need to know.

A1C records average blood glucose levels over a three-month period, but it can’t reveal the presence of high glucose episodes. In an average, those episodes may be balanced out by low blood sugar readings. Your blood glucose may appear to be well-controlled, but your diabetes management program might seem to be faltering.

It’s a fact that, in as many as 15% of patients, A1C scores are not accurately indicating actual glycemic control. You should be aware of the many factors that can affect your A1C number.

These include:

  • blood conditions such as anemia and sickle cell disease
  • malaria, HIV, cirrhosis and other liver conditions, heart disease, kidney disease, and hypothyroidism
  • blood loss, transfusions, and hemodialysis
  • certain drugs and medications, including alcohol, nicotine, opioids, aspirin therapy, and vitamin supplements

Click here for the scientific explanation.

Ask your doctor about GlycoMark

A1C testing alone isn’t a completely reliable indicator of your glycemic health. Only the GlycoMark test reflects recent (the previous two weeks) hyperglycemic excursions and can give you an indication of just how high your blood sugar spikes have been.

Even without complications, A1C can tell you only so much.  Ask your doctor about the GlycoMark test.


1Dungan KM, et al. Diabetes Care 2006 Jun; 29(6): 1214-1219.
2Selvin E, et al. Clin Chem. 2014 Nov; 60(11): 1409–1418.
3Selvin E, et al. Diabetes 2016;65:201–208.
4Lee AK, et al. Diabetes Care 2017 Dec; 40(12): 1661-1667.
5Rawlings AM, et al. Diabetes Care 2017 Jul; 40(7): 879-886.
6Nowak N, et al. Diabetologia 2013 Apr; 56(4): 709–713.


What Doctors Say

Testimonials WATCH HERE

Clinical guide

Find a Lab

Read our newsletter